Sitecore SMTP messages throw “device not ready” error

This was an odd one that came up during a recent project. My colleague Kevin had activated our standard Keystone workflow email notifications and configured the SMTP settings for the Sitecore application.

A short workflow test later and not only were emails not going out but an error was occurring with the message: “The device is not ready”. What is going on? Why is an IO error being thrown?

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